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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression.  This laboratory lesson allows students to conduct original research by characterizing...
    bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein
    Lesson
    4137

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    1477

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    Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers
    Most introductory genetics courses cover genetic linkage, a core concept in the CourseSource genetics learning outcome framework. Although it is a classical genetics topic, genetic linkage remains an important concept to understand in order to...
    meiosisphenotypegel electrophoresismicrosatellitesBanding PatternGenetic linkageInheritanceMolecular MarkersPhysical Linkage
    Lesson
    1040

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    365

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    Your Tax Dollars at Work: A mock grant writing experience centered on scientific process skills
    A successful scientist combines skill, creativity, and the art of persuasion to excel in his or her field of study. Critically important for the professional scientist is the ability to not only conduct research, but also to conceive a project and...
    researchexperimental designprocess of sciencePeer reviewgrant writingPecha Kuchaproposal
    Lesson
    2645

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    569

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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to conduct original research by identifying and...
    bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein
    Lesson
    1579

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    284

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    Authentic Ecological Inquiries Using BearCam Archives
    Learning through authentic scientific inquiries is essential for understanding the nature and process of science and for developing critical thinking and communication skills. It is logistically challenging, however, to offer experiences of...
    behaviorinterspecific interactionsPeer reviewauthentic inquiryintra-specific interactions
    Lesson
    1968

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    451

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    Air Quality Data Mining: Mining the US EPA AirData website for student-led evaluation of air quality issues
    Air pollution directly affects human health endpoints including growth, respiratory processes, cardiovascular health, fertility, pregnancy outcomes, and cancer. Therefore, the distribution of air pollution is a topic that is relevant to all, and...
    data miningenvironmental justiceair qualityairpollutionspatial reasoning
    Lesson
    1291

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    488

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    Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
    The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how scientists are able to unravel the molecular...
    pathwayscancerMolecular AlterationsRetrospective dataTumorigenesis
    Lesson
    1294

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    134

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    Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts
    Introductory physics courses are required for many programs in the life sciences, yet traditional curricula fail to help students meaningfully connect physical concepts with biological systems.  In this lesson, we describe an activity taught...
    quantitative biologyHIVmultiplicity of infectionPoisson DistributionPhysics for biologists
    Lesson
    7667

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    1039

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    Lights, Camera, Acting Transport! Using role-play to teach membrane transport
    Lights, Camera, Acting Transport! is an active and unique role-play exercise designed to teach introductory biology students basic concepts of passive and active membrane transport. The activity involves three acts in which students, representing...
    ATPcarrierschannelsco-transportelectrogenic pumpfacilitated diffusionmembrane transportpassive transportprimary active transportsimple diffusion
    Lesson
    2464

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    602

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    The Case of the Missing Strawberries: RFLP analysis
    While solving the fictional mystery of the missing strawberries, students are engaged in a guided-inquiry lesson featuring small-group and class discussions, hands-on activities, and laboratory exercises related to molecular genotyping by...
    process of scienceDNAforensicsgel electrophoresisMolecular genotypingRestriction endonucleaseRestriction enzymeRestriction fragment length polymorphismRFLP
    Lesson
    1460

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    439

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    Sex-specific differences in Meiosis: Real-world applications
    In traditional classrooms, students are typically presented with facts that they are asked to memorize and recall during an exam.  The rapid explosion of available scientific facts in recent years has made this model of teaching...
    meiosisReproductionAneuploidyGameteNon-disjunctionOocyteSpermTrisomy
    Lesson
    1668

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    290

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    Modeling the Research Process: Authentic human physiology research in a large non-majors course
    Laboratory experiences in large-enrollment introductory science courses often utilize “cookie-cutter style” laboratory experiences due to the relative simplicity of setting up the lab stations, as well as a need to teach students...
    data analysishypothesis testingexperimental designphysiology
    Lesson
    1450

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    277

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    Bad Cell Reception? Using a cell part activity to help students appreciate cell biology, with an improved data plan and no loss in coverage
    With a veritable myriad of cell parts to cover, it is easy for educators to become locked into marathon presentations that become taxing for both the instructor and the students. While we hope and expect that students master this material, the...
    primary literatureprokaryotesCell partsEukaryotesOrganelle functionOrganelles
    Lesson
    8676

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    1122

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    Why Meiosis Matters: The case of the fatherless snake
    A compelling reason to learn something can make all the difference in students’ motivation to learn it.  Motivation, in turn, is one of the key attitudes that drives learning.  This story presents students with a compelling puzzle of a...
    meiosismitosissex determinationAsexual reproductionParthenogenesis